The health system expects eClinicalWorks' platform to optimise its patient data management and expand access to its services.
The hospital will provide administrative leadership and strategic support for Lakeside Medical Center in Belle Glade.
The facility will have more than 20 storeys and is due to open in 2028.
The collaboration aims to identify the social care needs of the hospital's patient population.
NHS England uses public funding to deliver services but is not a government department itself.
Modern Pediatrics ensures its paediatricians are available for consultations via text messages.